The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs psychiatry criteria gh growthhormone sideeffects adhd antipsychotics anxiety attentiondeficithyperactivedisorder cd conduct endocin excess feedbackloop firstgeneration glftap glucocorticoids gravesdisease
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... • For pituitary ... Signs / Symptoms ... #SideEffects #endocrinology
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
and hypothalamic-pituitary-adrenal ... Psychological Symptoms ... PanicDisorder #Anxiety #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
etiology Signs/Symptoms ... pathophysiology #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
findings - For diagnosis ... have either 26 symptoms ... to 25 for new diagnosis ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... Pathophysiology #diagnosis
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
on hypothalamus/pituitary ... pathophysiology #signs #symptoms ... #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Hypothalamus -> Pituitary ... Extrapyramidal Symptoms ... #pharmacology #diagnosis
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