The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Major Depressive ... MajorDepressiveDisorder #Depression ... #MoodDisorders ... Signs #Symptoms #Psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
maintain this state Depressive ... Bipolar #Disorder #MoodDisorders ... Signs #Symptoms #Psychiatry
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
pathway -> Incr gene expression ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Seasonal Affective Disorder: Pathogenesis and clinical findings

Symptoms (included in the DSM-V) - Two Major Depressive episodes
DSM-V) - Two Major Depressive ... pattern with Major Depressive ... change from major depression ... AffectiveDisorder #MoodDisorders ... Signs #Symptoms #Psychiatry