The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis signs criteria sideeffects adhd antipsychotics anxiety attentiondeficithyperactivedisorder cd conduct feedbackloop firstgeneration gh glftap growthhormone hyperthyroidism macroadenoma masseffects mechanisms
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... • For pituitary ... Signs / Symptoms ... #SideEffects #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
and hypothalamic-pituitary-adrenal ... trigger Physical Symptoms ... Psychological Symptoms ... PanicDisorder #Anxiety #BehavioralDisorder ... #signs #psychiatry
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
have either 26 symptoms ... Hyperactivity-Impulsivity or >6 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #signs #psychiatry
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Hypothalamus -> Pituitary ... Extrapyramidal Symptoms ... pharmacology #diagnosis #psychiatry
Social Anxiety Disorder (SAD) - Pathophysiology Excessive fear of one or more social situations • Safety
• Behavioral Symptoms ... • Cognitive Symptoms ... derealization • Physical Symptoms ... SocialAnxiety #BehavioralDisorder ... #signs #psychiatry
Conduct Disorder (CD): Pathogenesis and clinical findings - Must have >3 symptoms present in the past
- Must have >3 symptoms ... months, with >1 symptom ... past 6 months - Symptoms ... #Conduct #CD #BehavioralDisorder ... #signs #psychiatry
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings - Must have >4 symptoms for >6 months,
- Must have >4 symptoms ... a sibling - Symptoms ... and vindictive symptoms ... OppositionalDefiant #ODD #BehavioralDisorder ... #signs #psychiatry
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