The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
spinal cord - Signs ... and Symptoms ... Ataxia (early sign ... weakness (late sign ... #symptoms #msk
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
#SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
#SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... and Symptoms ... • Spurling's sign ... pain Lasegue's sign ... #symptoms #pathophysiology
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
Pathogenesis and Symptoms ... cause the Positive Symptoms ... cause Negative Symptoms ... pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... and Symptoms Anaphylaxis ... Signs / Symptoms ... immunology #diagnosis #signs ... #symptoms
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... suicide Other Symptoms ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology