The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis signs symptoms msk allergy hypersensitivityreaction anaphylaxis orthopedics xlinked adhesivecapsulitis agammaglobulinemia anterior aqueoushumor avascularnecrosis c5c9deficiency cascade causes complement complications
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Recruitment • Humoral ... pathophysiology #immunology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... repeat exposure #Humoral ... pathophysiology #immunology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
deficiency in adaptive humoral ... pathophysiology #immunology
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings #SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
pathophysiology #immunology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Osteonecrosis Esp. humeral ... and femoral heads
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Dislocation • Humeral ... Posterosuperior humeral ... underlying bone of humeral ... Sachs Defect • Humeral
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy #Immunology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
pathophysiology #immunology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Impaction force from femoral ... Impaction force from femoral ... bone from the femoral
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
pathophysiology #immunology
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