The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Acute onset of skin ... symptoms in the acute ... Signs / Symptoms / Complications ... pathophysiology #immunology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... Tissue injury and inflammation ... , Carditis #Acute ... signs #symptoms #complications
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... : Complications ... Infection and inflammation ... Signs/Symptoms/Complications ... Balance Problems #Acute
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
cells recruited Complications ... : • Acute Asthma ... HypersensitivityReaction #Allergy #Immunology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... bacterial. => Inflammation ... resolve by 72 hours Complications
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic Hyperplasia ... FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... Hydronephrosis, Acute ... Benign #Prostatic #Hyperplasia
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Manifestations • Ocular - Inflammation ... • Cardiac - Inflammation ... acute phase reactant ... - Ligamentous inflammation ... Manifestations #Complications
Cholesteatoma (of middle ear): Pathogenesis and clinical findings
 • Congenital trapping of keratinizing epithelium in middle
Signs / Symptoms / Complications ... Polyp secondary to inflammation ... • Acute otitis ... signs #diagnosis #complications