The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... -> Incr local inflammation ... Manifestations #pathophysiology ... diagnosis #signs #symptoms ... #complications
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic ... activation of inflammatory ... bladder stones #BPH ... #Benign #Prostatic ... Hyperplasia #Prostate #Pathophysiology
Psoriatic Arthritis: Complications

 • Ocular - Inflammation of middle layer of the eye (the uvea, which
• Ocular - Inflammation ... Valvular disease - Inflammatory ... PsoriaticArthritis #pathophysiology ... diagnosis #signs #symptoms ... #Complications
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... Decreased Prostatic inflammation ... #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
tumour, stone, BPH ... (neurogenic), inflammation ... Incr PVR if a complication ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
clinical findings and complications ... Activity -> Incr BP ... BZD #withdrawal #pharmacology ... #pathophysiology ... diagnosis #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... Manifestations #Complications ... #pathophysiology ... diagnosis #signs #symptoms