The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology signs complications manifestations otitismedia adhesivecapsulitis anaphylaxis benign bph centralretinalartery cholesteatoma chondrocalcinosis cppd crao disease extraarticular frozenshoulder hyperplasia lupus mastoiditis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... in the acute phase ... pathophysiology #immunology ... #diagnosis #signs ... #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
endoscopy (Not Inflammatory ... acute phase reactant ... lung fibrosis #AnkylosingSpondylitis ... pathophysiology #diagnosis ... #signs #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... Tissue injury and inflammation ... , Carditis #Acute ... pathophysiology #diagnosis ... #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... mucosa leads to inflammation ... : Extension of inflammatory ... pathophysiology #signs #symptoms ... #diagnosis #otology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... scaling that extend inflammation ... -> Incr local inflammation ... pathophysiology #diagnosis ... #signs #symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... pathophysiology #diagnosis ... #symptoms #signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... trucking" • Acute ... ophthalmology #diagnosis ... #signs #symptoms
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Acute Otitis Media ... Infection and inflammation ... severe Signs/Symptoms ... pathophysiology #symptoms ... #signs #diagnosis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
• Non-specific Acute-phase ... • Rate of inflammatory ... etc • Systemic inflammation ... pathophysiology #signs #symptoms ... #diagnosis
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... activation of inflammatory ... Hydronephrosis, Acute ... #Diagnosis
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