The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology complications extraarticular manifestations psoriaticarthritis ra rheumatoidarthritis vasculitis acute adhesivecapsulitis ankylosingspondylitis benign bph centralretinalartery chondrocalcinosis cppd crao disease frozenshoulder
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... mutation) that alter inflammatory ... yrs old; F>M Signs ... /Symptoms: - Fever ... #Symptoms #Vasculitis
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Infection and inflammation ... becomes more severe Signs ... /Symptoms/Complications ... Problems #Acute #OtitisMedia ... #signs #diagnosis
Reactive Arthritis • Inflammation of joints (commonly large joints) - Asymmetric Oligoarthritis: Joint
Reactive Arthritis ... • Inflammation ... Effusions • Inflammation ... pathophysiology #diagnosis #signs ... #symptoms
Psoriatic Arthritis: Pathogenesis and Clinical findings In tendons and connective tissues: • Enthesitis - Pain/tenderness over
Psoriatic Arthritis ... • Dactylitis - Inflammation ... Arthritis of DIP ... pathophysiology #diagnosis #signs ... #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... manifestations Skin: • Inflammation ... Eyes: • Globe inflammation ... pathophysiology #signs ... #symptoms #diagnosis
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
. => Inflammation ... mechanisms) #OtitisMedia ... pathophysiology #diagnosis #symptoms ... #signs #peds #pediatrics
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... scaling that extend inflammation ... -> Incr local inflammation ... pathophysiology #diagnosis #signs ... #symptoms #complications
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... • Rate of inflammatory ... etc • Systemic inflammation ... Extra-articular signs ... #symptoms #diagnosis
Psoriatic Arthritis: Complications • Ocular - Inflammation of middle layer of the eye (the uvea, which
Psoriatic Arthritis ... • Ocular - Inflammation ... Valvular disease - Inflammatory ... pathophysiology #diagnosis #signs ... #symptoms #Complications
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
mastoid air cells (inflammation ... mucosa leads to inflammation ... : Extension of inflammatory ... pathophysiology #signs ... #symptoms #diagnosis
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