The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis menstrualcycle ovariancycle signs symptoms psychiatry pituitary feedbackloop gh growthhormone pharmacology sideeffects urology uterinecycle 21hydroxylasedeficiency 21ohd anticonvulsants arthropathy benign benzodiazepines
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
activity -> Dose-dependent ... Sedation, dose-dependent ... #SideEffects #Pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
A good mnemonic ... #SideEffects #endocrinology ... #mnemonic #GLFTAP ... #pathophysiology
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings • Difficulties with Activities - Initiation Of projects
Dependent Personality ... themselves DPD Mnemonic ... self #DPD #Dependent ... Signs #Symptoms #Mnemonic
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology ... #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
GravesDisease #pathophysiology ... #endocin #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... signs #symptoms #endocrinology ... #pathophysiology
Benzodiazepines: Mechanism of Action and Side Effects • Decr spinal cord activity -> Muscle relaxant
, weakness - Dependence ... #Pharmacology #pathophysiology
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
#FeedbackLoop #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
#FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
#OvarianCycle #pathophysiology ... #menstruation #endocrinology
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