The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis pediatrics peds syndrome 21hydroxylasedeficiency 21ohd bulimianervosa caudaequina endocrinology erythematosus femoralhead frozenshoulder gait lupus musculoskeletal orthopedics pagetsdisease praderwilli psychiatry
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... #msk #diagnosis ... pathophysiology #signs ... #symptoms #orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... PraderWilli #Syndrome #genetics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... #signs
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... a stroke that caused ... pathophysiology #diagnosis #symptoms ... #signs #stages ... #staging #msk
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... pathophysiology #genetics
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Greater Trochanter Fracture ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... and Symptoms Associated ... / Behavioural Features ... related to complications ... Sores, scars, calluses
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... pathophysiology #diagnosis #signs ... #symptoms #complications
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