The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... => Microscopic fractures ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Sacral compression fracture ... bilateral rami fractures ... #Orthopedics #MSK ... #diagnosis #complications ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... #msk #diagnosis ... #pathophysiology ... #signs #symptoms
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... XR — scotty dog sign ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology ... #signs #symptoms
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... CubitalTunnel #Syndrome #Diagnosis ... #pathophysiology ... #signs #symptoms ... #msk
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... abscess • High grade ... Complications #pathophysiology ... #symptoms #signs ... #diagnosis
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... and Symptoms ... Radiculopathy #MSK ... #diagnosis #signs ... #symptoms #pathophysiology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Acute onset of skin ... Signs / Symptoms ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... /Symptoms: - Pretibial ... GravesDisease #pathophysiology ... #signs #diagnosis