The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... diagnosis #symptoms #signs
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... diagnosis #symptoms #signs ... stages #staging #msk
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
activity that causes ... pathophysiology #diagnosis #signs ... #symptoms #msk
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... middle ear bones causes ... pathophysiology #diagnosis #signs
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
Genetics: concordance rates ... pathophysiology #diagnosis #signs ... symptoms #psychiatry #RiskFactors
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
purging, high rates ... pathophysiology #diagnosis #signs ... symptoms #psychiatry #RiskFactors
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
age 10), but the rates ... physical fights • Uses ... weapon that can cause ... diagnosis #symptoms #signs