The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Sacral compression fracture ... bilateral rami fractures ... 2 - Rami fracture ... posterior ilium fracture ... #Orthopedics #MSK
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk ... pathophysiology #symptoms #signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... onto lateral hip Signs ... • Non-union of fracture ... #msk #diagnosis ... pathophysiology #signs
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... XR — scotty dog sign ... Spondylolisthesis #MSK ... pathophysiology #signs
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Syndrome Signs ... Incr Skeletal fractures
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Greater Trochanter Fracture ... causes #symptoms #signs ... #diagnosis #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... diagnosis #symptoms #signs ... stages #staging #msk
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
Genetics: concordance rates ... pathophysiology #diagnosis #signs ... symptoms #psychiatry #RiskFactors
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... -> Pathologic fractures ... pathophysiology #diagnosis #signs
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
increased risk of fracture ... warmth) GENERAL FEATURES ... highest mortality rates ... pathophysiology #diagnosis #signs