The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... subthreshold mechanical loading ... from continued loading ... Stress Fracture ... StressFractures #msk
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports ... #MSK #orthopedics ... #Grading #Grades
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Sacral compression fracture ... bilateral rami fractures ... Classification #Grades #Grading ... #Orthopedics #MSK
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... in elderly Causes ... #msk #orthopedics ... #differential #causes
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... cause quadriplegia ... within GI and URT causes ... lymph -> Koplik's spots ... vessel collapse leading
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... ischemia -> Venous beading ... retinal ischemia causes
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Greater Trochanter Fracture ... pathophysiology #causes ... signs #diagnosis #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... a stroke that caused ... stages #staging #msk
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... bone formation MSK ... -> Pathologic fractures ... Skull expansion causes ... middle ear bones causes
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... chondrocytes at fracture ... Fluoroquinolones - Causes ... #Orthopedics #msk