The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs complications ophthalmology psychiatry orthopedics retinopathy syndrome acute adhesivecapsulitis alcoholusedisorder aseptic bulimianervosa caudaequina cecs centralretinalartery childhood chronic chronicexertional
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports ... #MSK #orthopedics ... #Grading #Grades
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... pathophysiology #symptoms
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... hemorrhagic rash; symptoms ... lymph -> Koplik's spots ... vessel collapse leading ... non-specific viral symptoms
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
with possible symptoms ... pain • Palpable grinding ... diagnosis #signs #symptoms ... #msk
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... -> Cotton-wool Spots ... -> Elschnig's Spots ... diagnosis #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis #symptoms
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
- Alcohol craving ... • Withdrawal symptoms ... , tachycardia, nausea ... Diagnosis #Signs #Symptoms
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... ischemia -> Venous beading ... retinal ischemia causes
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
lights are a key symptom ... • Significant cause ... most frequent cause ... Increased pressure gradient ... blindness Signs / Symptoms
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