The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis orthopedics signs symptoms anorexianervosa discherniations femoralhead genetics gustiloanderson lowanklesprain open pagetsdisease pediatrics peds pelvicring praderwilli psychiatry sports stressfractures
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... and Complications ... #Classification ... #Grades #Grading ... #Orthopedics #MSK
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Open Fractures: ... and Complications ... Gustilo-Anderson Classification ... #Open #Fractures ... #MSK #Orthopedics
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... subthreshold mechanical loading ... from continued loading ... Stress Fracture ... StressFractures #msk
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Signs/Symptoms/Complications ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
Pathogenesis and Complications ... -> Mechanical loading ... DiscHerniations #complications ... #msk #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Signs/Symptoms/Complications ... Incr Skeletal fractures
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
Anorexia Nervosa: Complications ... increased risk of fracture ... Death - Cardiac complications ... highest mortality rates ... AnorexiaNervosa #Complications
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... signs #symptoms #complications
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