The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Spondylosis - Pathogenesis and Complications

Vertebral disease that may compress the vertebral canal from all sides
Note: Do
Pathogenesis and Complications ... #Spondylosis #pathophysiology ... #msk #complications
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... tumour causing injury ... Acute #SpinalCord #Injury ... Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Clinical Features and Complications ... Typically "inside out" injury ... Fractures #Diagnosis #Complications ... #MSK #Orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... Signs/Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... possible vascular injury ... - Type 1 or 2 injury ... #Orthopedics #MSK ... #pathophysiology
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
Pathogenesis and Complications ... DiscHerniations #complications ... #msk #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
cells -> Tissue injury ... Pancarditis and valvular injury ... RheumaticFever #pathophysiology ... signs #symptoms #complications
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... Signs / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... cause quadriplegia ... evasion techniques cause ... > Inflammation causes ... peds #pediatrics #pathophysiology