The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms orthopedics complications menstrualcycle ovariancycle fractures ophthalmology classification comparison diabetes differential gh grades grading growthhormone pediatrics peds pituitary
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... below level of injury ... Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
most commonly injured ... (uncommonly injured ... LowAnkleSprain #Sports ... #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... Tetanus Toxin -> Spores ... metabolites induce injury ... lymph -> Koplik's spots ... peds #pediatrics #pathophysiology
RICE: Mechanism of Action Rest (weight bearing or stressful motion discontinued) Ice (applied to injury) Compression (wrap applied to
Ice (applied to injury ... wrap applied to injured ... heart) #RICE #Sports ... #pathophysiology ... #mechanism #MSK
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings Classification of PCL Iniuries • Partial: Translation <
Ligament (PCL) Injury ... Some sort of end ... PCL: The PCL is injured ... PosteriorCruciateLigament #PCL #Injury ... #MSK #Sports #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... signs #symptoms #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
ovulation -> LH supports ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
deficiency: - Short ... #FeedbackLoop #endocrinology ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology
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