The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms fractures complications hypersensitivityreaction staging adhesivecapsulitis classification differential disruptors femoralhead femur frozenshoulder gait grades grading healing pagetsdisease pelvicring
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... of allergen-specific ... Allergic reaction ... T-Cell activation takes ... #Immunology #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk ... #orthopedics #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... in elderly Causes ... #msk #orthopedics ... #differential #causes ... #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #msk #diagnosis ... #pathophysiology ... signs #symptoms #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Grade 2 - Rami fracture ... Grades #Grading #Orthopedics ... #MSK #diagnosis ... complications #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... a stroke that caused ... side) Second Stage ... FrozenShoulder #pathophysiology ... #staging #msk
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... Fluoroquinolones - Causes ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Greater Trochanter Fracture ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... signs #diagnosis #msk
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... bone formation MSK ... -> Pathologic fractures ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology
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