The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs psychiatry lupus orthopedics sle withdrawal achilles adhesivecapsulitis alcohol alzheimersdisease aseptic caudaequina cecs chronic chronicexertional compartmentsyndrome dementia erythematosus etoh
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... / Complications ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
lateral hip Signs/Symptoms ... /Complications: ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
etiology Signs/Symptoms ... /Complications: ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... chromosome 21) Signs / Symptoms ... / Complications ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... related to complications ... Sores, scars, calluses ... inducing vomiting #BulimiaNervosa ... pathophysiology #diagnosis
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... ophthalmology #diagnosis ... #signs #symptoms ... #complications
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... Symptoms can take ... Gastrointestinal distress (nausea ... Pathophysiology #Diagnosis ... #Signs #Symptoms
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