The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms diabetes ophthalmology orthopedics acute caudaequina classification closedangle diabetic diabeticfoot discherniations erythematosus fractures glaucoma lowanklesprain lupus musculoskeletal
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... 2.5cm - APC Grade ... #Grading #Orthopedics ... #MSK #diagnosis ... #complications
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
Pathogenesis and Complications ... -> Mechanical loading ... DiscHerniations #complications ... #msk #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... Signs / Symptoms / Complications ... CaudaEquina #Syndrome #MSK
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
ischemia -> Venous beading ... retinal ischemia causes ... ophthalmology #diagnosis #complications
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• Significant cause ... most frequent cause ... Increased pressure gradient ... Signs / Symptoms / Complications
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Glycosylation - AGE cause ... in inopportune loading ... pathophysiology #complications
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... signs #symptoms #complications
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