The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Trendelenburg Gait ... Trendelenburg Gait ... #pathophysiology ... #causes #symptoms ... signs #diagnosis #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
paresthetica • Symptoms ... 3-6 months of symptom ... abnormalities (gait ... MeralgiaParesthetica #MSK ... #pathophysiology
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
etiology Signs/Symptoms ... rupture - Antalgic gait ... diagnosis #signs #symptoms ... #pathophysiology ... #msk #orthopedics
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Dysfunction, Weight gain ... Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... Diagnosis #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... tolerance • Weight gain ... diagnosis #signs #symptoms ... endocrinology #pathophysiology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... stages #staging #msk
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
activity that causes ... CompartmentSyndrome #CECS #pathophysiology ... diagnosis #signs #symptoms ... #msk
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms