The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk ... pathophysiology #symptoms #signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Avulsion or shearing injury ... onto lateral hip Signs ... #msk #diagnosis ... pathophysiology #signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... spinal artery injury ... weakness and #Acute ... pathophysiology #signs ... #symptoms #msk
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... spinal cord - Signs ... Ataxia (early sign ... weakness (late sign ... #symptoms #msk
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
possible vascular injury ... bilateral rami fractures ... Grade 2 - Rami fracture ... - Type 1 or 2 injury ... #Orthopedics #MSK
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open Fractures: ... Mechanisms, Clinical Features ... Typically "inside out" injury ... Classification #Open #Fractures ... Complications #MSK
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... XR — scotty dog sign ... Spondylolisthesis #MSK ... pathophysiology #signs
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... cells -> Tissue injury ... Pancarditis and valvular injury ... , Carditis #Acute ... pathophysiology #diagnosis #signs
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... TendonRupture #diagnosis #signs ... pathophysiology #msk
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... Dislocation #Diagnosis #signs ... #symptoms #msk