The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... Recurrent use of alcohol ... craving - Intense ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... pathophysiology #diagnosis ... #signs #symptoms ... #msk
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Oscillation between mood states ... distractibility - racing ... maintain this state ... MoodDisorders #Diagnosis ... Pathophysiology #Signs
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
side) Second Stage ... pathophysiology #diagnosis ... #symptoms #signs ... #stages #staging ... #msk
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
- History of alcohol ... Constipation - MSK ... Refeeding #Syndrome #diagnosis ... pathophysiology #symptoms #signs
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... - Tobacco & Alcohol ... #Orthopedics #msk ... pathophysiology #diagnosis
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... The onset of alcohol ... Life-threatening state ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... Nephrolithiasis (Kidney Stones ... pathophysiology #diagnosis ... #signs #symptoms