The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... Recurrent use of alcohol ... craving - Intense ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... distractibility - racing ... maintain this state ... MoodDisorders #Diagnosis ... Pathophysiology #Signs
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... pathophysiology #diagnosis ... #signs #symptoms ... #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
with autoimmune disorders ... pathophysiology #diagnosis ... #symptoms #signs ... #stages #staging ... #msk
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
Obsessive-Compulsive Disorder ... Obsessive-Compulsive Disorder ... thoughts, ideas, images ... PersonalityDisorder #Diagnosis ... #Psychiatry #Signs
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
- History of alcohol ... Constipation - MSK ... Refeeding #Syndrome #diagnosis ... pathophysiology #symptoms #signs
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Panic Disorder: ... heritability >> Panic Disorder ... exercise, caffeine, alcohol ... Pathophysiology #diagnosis ... #symptoms #signs
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... - Tobacco & Alcohol ... Metabolic / Endocrine disorders ... #Orthopedics #msk ... pathophysiology #diagnosis
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings
 • Arrogant, Haughty Behaviors or Attitude - Often display
Narcissistic Personality Disorder ... positive self-states ... PersonalityDisorder #Diagnosis ... Psychiatry #Criteria #Signs
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... The onset of alcohol ... Life-threatening state ... Pathophysiology #Diagnosis ... #Signs #Symptoms