The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis signs symptoms adhesivecapsulitis bipolar comparison complications contractures degenerative differential disorder disruptors dupuytrens fracture frozenshoulder glaucoma healing inflammatory jointdisease
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... ligaments First stage ... side) Second Stage ... movement) Third Stage ... #staging #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
intervertebral disc disease ... Tingling, Burning, Stinging ... , Stabbing) - ... MeralgiaParesthetica #MSK
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
Oscillation between mood states ... variability in disease ... - Incr risk taking ... maintain this state
Overuse Tendinopathy: Pathogenesis and clinical findings • Intrinsic factors: Age, Body weight, Nutrition, Gender, Anatomical variations,
Overuse Tendinopathy ... laxity, Systemic disease ... conditions #Overuse ... pathophysiology #msk
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees) • Incr Axial rotation of thoracic
Iliac Crests, Shoulders ... Restrictive Pulmonary Disease ... pathophysiology #msk
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Inflammatory Joint Disease ... Lots of fluid, takes ... Degenerative Joint Disease ... Comparison #Versus #MSK
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... stability Hard Callus Stage ... #Orthopedics #msk ... #Staging #pathophysiology
Dupuytren’s Disease: Pathogenesis and Clinical Findings • Aging, smoking and/or diabetes -> Microangiopathy and palmar fascia
Dupuytren’s Disease ... Clinical Findings • Aging ... #Dupuytrens #Disease ... pathophysiology #msk
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... bone formation MSK ... Nephrolithiasis (Kidney Stones
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings • Risk factors -> Incr IOP, Incr age, African-American
myopia, vascular disease ... peri-papillary RNFL imaging ... defects => End-stage
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