The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis menstrualcycle ovariancycle comparison complications grades grading injury orthopedics signs symptoms uterinecycle acl agerelated anteriorcruciateligament caudaequina causes childhood discherniations feedbackloop
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... ESR, RF, ANA) Degenerative ... > Stiffness is short-lived ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
C6/7 Aging ->Degeneration ... complications #msk ... #pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
• Large lumbar degenerative ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
ovulation -> LH supports ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
deficiency: - Short ... #FeedbackLoop #endocrinology ... #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
around the hip • Degeneration ... Trendelenburg #Gait #pathophysiology ... signs #diagnosis #msk
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... #Orthopedics #MSK ... complications #pathophysiology
Age Related Macular Degeneration: Pathogenesis and clinical findings Photoreceptor atrophy -> Extracellular debris (drusen) from RPE atrophy/metabolism
Related Macular Degeneration ... - Faded/blind spots ... MacularDegeneration #pathophysiology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
days long) • Starts ... follicle (others degenerate ... #OvarianCycle #pathophysiology ... #comparison #endocrinology
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