The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... Pathogenesis and clinical findings ... => Microscopic fractures ... loading Stress Fracture ... StressFractures #msk
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... Pathogenesis and clinical findings ... low energy fall fractures ... Atypical femur fracture ... #msk #orthopedics
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
arthritis (RA): X-ray features ... different planes) #RheumatoidArthritis ... Pathophysiology #Findings
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Pathogenesis and clinical findings ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
Pathogenesis and Clinical Findings ... interarticularis stress fracture ... Spondylolisthesis #MSK
Osteoarthritis (OA): X-ray features 
 - Joint space narrowing (least specific)
 - Subchondral Cysts (pockets of
Osteoarthritis (OA): X-ray features ... bone deposits/spurs ... radiology #diagnosis #findings
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Pathomechanics and Clinical Findings ... LowAnkleSprain #Sports ... #MSK #orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical findings ... Incr Skeletal fractures ... • Short stature
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical findings ... Greater Trochanter Fracture ... signs #diagnosis #msk
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Joint diseases features ... Stimulation of nerve endings ... Extra-articular signs #RheumatoidArthritis