The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis complications orthopedics pediatrics classification grades injury ophthalmology retinopathy signs symptoms syndrome acl anteriorcruciateligament childhood comparison degenerative diabetes diabetic
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports ... #MSK #orthopedics ... #Grading #Grades
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... signs #symptoms #msk
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
-> Mechanical loading ... complications #msk
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
fractures • Short ... pathophysiology #peds
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... ischemia -> Venous beading
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification #Grades #Grading ... #Orthopedics #MSK
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... vessel collapse leading ... #Immunization #peds
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
> Stiffness is short-lived ... Comparison #Versus #MSK
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
metabolic demand of growing ... branching of vessels leading ... #Prematurity #peds
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