The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... focal melting) -> Retinopathy ... • Loss of the eye ... #Xeropthalmia #pathophysiology ... #ophthalmology
Astigmatism: Pathogenesis and clinical findings
Astigmatism - deviation from spherical curvature of the lens or eye

Refracting power
Astigmatism: Pathogenesis ... of the lens or eye ... • Headache • Ocular ... #pathophysiology ... #ophthalmology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
all coats of the eye ... - Impinges on ocular ... Impaired extra-ocular ... Orbital #Cellulitis #pathophysiology ... #ophthalmology
Trachoma: Pathogenesis and clinical findings

 • Environmental Factors -> Bacterial infection is encouraged by poor hygiene
Transmission -> Eye-seeking ... from nasal or ocular ... Lubrication • Dry eye ... Trachoma #Chlamydia #pathophysiology ... #ophthalmology
Onchocerciasis “River Blindness”: Pathogenesis and Ocular Manifestations
Vectorial Transmission
-> Onchocerca volvulus, a parasitic helminth, matures in to
Pathogenesis and Ocular ... Microfilariae enter the eye ... RiverBlindness #pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... present with a red eye ... -> crowding of ocular ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive Retinopathy ... vasoconstrictive • Acute ... #Hypertensive #Retinopathy ... #pathophysiology ... #ophthalmology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Note: Eye exam ... normal: - extra-ocular ... If the eye cannot ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology
Retinopathy of Prematurity: Pathogenesis and clinical findings
Increased metabolic demand of growing eye
-> Excessive VEGF production ->
Retinopathy of Prematurity ... demand of growing eye ... detachment #Retinopathy ... peds #pediatrics #pathophysiology ... #ophthalmology
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Manifestations • Ocular ... visual acuity, eye ... - Inflammation acute ... lung fibrosis #AnkylosingSpondylitis ... Complications #pathophysiology