The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Achilles Tendon ... findings • The Achilles ... in the body • Achilles ... rupture of the Achilles ... pathophysiology #msk #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
cyclist) - APC Grade ... 2.5cm - APC Grade ... ligaments - APC Grade ... auto) - LC Grade ... #Grading #Orthopedics
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
#Sports #MSK #orthopedics ... #Grading #Grades
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
reaction, Myasthenia Gravis ... , Graves' Disease
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Enthesitis: Commonly Achilles
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
prominently in Achilles
Necrotizing Fasciitis: Pathogenesis and Clinical Findings

#NecrotizingFasciitis #pathophysiology #orthopedics
pathophysiology #orthopedics
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
StressFractures #msk #orthopedics
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease:
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi