The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis antipsychotics complications hyperuricemia mechanisms pharmacology psychiatry sideeffects anteriorcruciateligament closedangle compartmentsyndrome cppd disease firstgeneration glaucoma injury msk ophthalmology pseudogout
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... throughout body (mouth, gut ... bradykinesia/akinesia • Acute
Gout: Pathogenesis and Clinical Findings - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders -
Gout: Pathogenesis ... Medications (ASA, ACE ... Chronic tophaceous gout ... Complications #Gout
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis ... Disease - Acute ... to crystals -> Acute ... ) (tends to be out ... e.g., wrist) #Chondrocalcinosis
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
renal tubules - ACE-inhibitors ... Complications #Gout
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings • Feeling a "pop" • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... knee is "giving out ... AnteriorCruciateLigament #ACL
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... must be ruled out ... bodies, shallow ACD ... Photophobia #Acute
Second Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
As such, it is considered ... Antagonism - Block ACh ... Gut, mouth, eyes
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