The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis msk complications grades retinopathy secondary signs symptoms acute cataracts classification closedangle diabetes diabetic fracture fractures healing lowanklesprain openangle pediatrics
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk #orthopedics ... #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle Glaucoma ... present with early glaucoma ... Increased pressure gradient ... #pathophysiology ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
• Secondary glaucoma ... Retinoblastoma #pathophysiology ... #ophthalmology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification #Grades #Grading ... #Orthopedics #MSK ... complications #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
ischemia -> Venous beading ... Retinopathy #Diabetes #ophthalmology ... complications #pathophysiology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... ) • Fracture disrupts ... Healing #Stages #Orthopedics ... #msk #Staging #pathophysiology ... #diagnosis #disruptors
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
metabolic demand of growing ... branching of vessels leading ... peds #pediatrics #pathophysiology ... #ophthalmology
Secondary Glaucoma: Pathogenesis and Clinical Findings Open-Angle Secondary Glaucoma: • Pre-trabecular defect -> Aqueous outflow is obstructed
Secondary Glaucoma ... Open-Angle Secondary Glaucoma ... => Secondary glaucoma ... #pathophysiology ... #ophthalmology
Cataract: Pathogenesis and clinical findings Increased Age (most common) -> Ultraviolet light, radiation, toxins ->Denaturation and abnormal
angle closure glaucoma ... #cataracts #pathophysiology ... #ophthalmology
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