The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Subjective Tinnitus: Pathogenesis and clinical findings
Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
refers to sound caused ... #Tinnitus #Causes ... #pathophysiology ... #differential #
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
) • Fracture disrupts ... Metabolic / Endocrine disorders ... Fluoroquinolones - Causes ... Healing #Stages #Orthopedics ... #msk #Staging #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
relapse of bipolar disorder ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... , tachycardia, nausea ... AlcoholUseDisorder #EtOH #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Lympho-proliferative disorders ... Release of purine bases ... Hyperuricemia #Pathophysiology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Pathogenesis • Bipolar Disorder ... Manic #Secondary #Causes ... #Differential # ... Diagnosis #Pathophysiology
Acquired Disorders of Reduced Bone Strength: Pathogenesis
 • Hyperparathyroidism
 • Vitamin D deficiency
 • Malabsorption syndromes
Acquired Disorders ... Diabetes • Other causes ... Sedondary #Acquired #Disorders ... #BoneStrength #pathophysiology ... #differential #
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
with autoimmune disorders ... a stroke that caused ... FrozenShoulder #pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
Deficit Hyperactive Disorder ... their turn • Causes ... BehavioralDisorder #Pathophysiology