The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis msk signs symptoms fractures anorexianervosa grading psychiatry acute causes classification femoralhead femur genetics lowanklesprain otitismedia pagetsdisease pediatrics peds pelvicring
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Clinical Features and Complications ... #Grading #Orthopedics ... MSK #diagnosis #complications ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Avulsion or shearing ... Signs/Symptoms/Complications ... msk #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... (and disruptors ... #Fracture #Healing ... #Stages #Orthopedics ... #msk #Staging #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Otitis Media: Complications ... (uncommon) • Hearing ... abscess • High grade ... Otalgia (Ear Pain) fades ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
ligament substance leading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Signs/Symptoms/Complications ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... -> Pathologic fractures ... -> Conductive hearing ... PagetsDisease #pathophysiology ... signs #symptoms #complications
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
Anorexia Nervosa: Complications ... increased risk of fracture ... Death - Cardiac complications ... highest mortality rates ... #pathophysiology
Anorexia Nervosa: Pathogenesis and Risk Factors Biological Risk Factors • Gender: F > M • Genetics: concordance
Genetics: concordance rates ... Neurobiology: disruptions ... female body as having ... AnorexiaNervosa #pathophysiology
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