The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
cyclist) - APC Grade ... 2.5cm - APC Grade ... ligaments - APC Grade ... auto) - LC Grade ... #Grading #Orthopedics
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... etiology Signs/Symptoms ... endocrinology #symptoms
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
StressFractures #msk #orthopedics ... pathophysiology #symptoms
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
#Sports #MSK #orthopedics ... #Grading #Grades
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Syndrome Signs/Symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
lateral hip Signs/Symptoms ... pathophysiology #signs #symptoms ... #orthopedics
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
severe Signs/Symptoms ... abscess • High grade ... Otalgia (Ear Pain) fades ... pathophysiology #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
etiology Signs/Symptoms ... diagnosis #signs #symptoms ... pathophysiology #msk #orthopedics
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
reaction, Myasthenia Gravis ... , Graves' Disease
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
paresthetica • Symptoms ... 3-6 months of symptom ... sensory nerve, thus symptoms ... mass Sensory Symptoms ... diagnosis #signs #symptoms