The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis psychiatry msk peds genetics syndrome vasculitis 21hydroxylasedeficiency 21ohd achilles acute adhd alzheimersdisease anterior anxiety arteritis attentiondeficithyperactivedisorder cd cecs chronicexertional
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... suicide Other Symptoms ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
at > 17 years old ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #signs #psychiatry ... #criteria
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
patients < 50 yrs old ... ; F>M Signs/Symptoms ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology ... #msk #orthopedics
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Deficiency (21-OHD ... degrees of 21-OHD ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds #pediatrics
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