The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
cartilage means direct contact ... Osteoarthritis #OA #pathophysiology ... diagnosis #signs #symptoms ... #complications
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... diagnosis #signs #symptoms ... #complications
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
feet Signs/Symptoms ... /Complications: ... Criteria #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Biomechanical Factors • Contact ... Keratoconus Signs / Symptoms ... / Complications ... #Keratoconus #pathophysiology
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Conduct Disorder ... - Must have >3 symptoms ... fire setting) #Conduct ... #CD #BehavioralDisorder ... #Pathophysiology
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
- Must have >4 symptoms ... a sibling - Symptoms ... to progress to conduct ... OppositionalDefiant #ODD #BehavioralDisorder ... #Pathophysiology