The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... Biomechanical Factors • Contact ... #Keratoconus #pathophysiology ... #ophthalmology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... signs #psychiatry #criteria
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Stevens-Johnson Syndrome ... • Contact Dermatitis ... Allergy #Immunology #pathophysiology
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Conduct Disorder ... >18 years old, criteria ... fire setting) #Conduct ... #CD #BehavioralDisorder ... #Pathophysiology
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
to progress to conduct ... OppositionalDefiant #ODD #BehavioralDisorder ... #Pathophysiology ... signs #psychiatry #criteria
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
Exertional Compartment Syndrome ... • Diagnostic criteria ... CompartmentSyndrome #CECS #pathophysiology
Cataract: Pathogenesis and clinical findings

Increased Age (most common) -> Ultraviolet light, radiation, toxins ->Denaturation and abnormal
Iris-trabecular meshwork contact ... #cataracts #pathophysiology ... #ophthalmology
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Findings Serotonin Syndrome ... Serotonin Toxicity Criteria ... #Serotonin #Syndrome ... #Pathophysiology