The Calgary Guide to Understanding Disease @TheCalgaryGuide
549.6K 392 153
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
Contributor Ranks
Latest Searches
190 results
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
palpation - Vasculitic ... Temporal #Arteritis #Pathophysiology ... Signs #Symptoms #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Complications #pathophysiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Leukocytoclastic vasculitis ... Cutaneous small vessel vasculitis ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
PolyarteritisNodosa #Pathophysiology ... Signs #Symptoms #Vasculitis
Diabetic Nephropathy: Pathogenesis
 - Metabolic Pathway
 - Hemodynamic Pathway

#Diabetic #Nephropathy #Diabetes #pathophysiology
Nephropathy #Diabetes #pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... RheumatoidArthritis #RA #pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
PM #Diagnosis #Pathophysiology ... Signs #Symptoms #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology