The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Falls: Pathogenesis and Complications
Poly-pharmacy
Disorders affecting movement and balance
 - Sensory deficits
 - Neuromuscular degeneration/Cerebrovascular disease
 -
Pathogenesis and Complications ... Lifestyle #Geriatrics ... #Falls #pathophysiology ... #complications ... #diagnosis
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Signs/Symptoms/Complications ... #pathophysiology ... #endocrinology
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Clinical Features and Complications ... Open #Fractures #Diagnosis ... #Complications ... #MSK #Orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Signs/Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Signs/Symptoms/Complications ... TendonRupture #diagnosis ... signs #symptoms #pathophysiology ... #msk #orthopedics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology ... signs #symptoms #diagnosis
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... Grades #Grading #Orthopedics ... #MSK #diagnosis ... #complications ... #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis ... #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Signs / Symptoms / Complications ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis