The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms classification disruptors femoralhead fracture genetics grades grading ophthalmology otitismedia pagetsdisease pelvicring praderwilli prematurity stages staging syndrome
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... Signs/Symptoms/Complications ... #msk #diagnosis ... #pathophysiology ... signs #symptoms #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
and Complications ... Grades #Grading #Orthopedics ... #MSK #diagnosis ... #complications ... #pathophysiology
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
Retinopathy of Prematurity ... -> Neovascular complications ... branching of vessels leading ... #Prematurity #peds ... #pediatrics #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
resolve by 72 hours Complications ... TM perforation, hearing ... #OtitisMedia #pathophysiology ... symptoms #signs #peds ... #pediatrics
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... #Fracture #Healing ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... -> Conductive hearing ... PagetsDisease #pathophysiology
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