The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... => Microscopic fractures ... => Fracture propagation ... loading Stress Fracture ... StressFractures #msk
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Grade 2 - Rami fracture ... #Orthopedics #MSK ... #diagnosis #complications ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis ... #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Atypical femur fracture ... Subtrochanteric #Femur #Fractures ... #msk #orthopedics
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open Fractures: ... and Complications ... Classification #Open #Fractures ... #Diagnosis #Complications ... #MSK #Orthopedics
Clavicular Fracture: Pathogenesis and clinical findings

Group I (69%) - Middle third (mid-shaft)
Group II (29%) - Distal
Clavicular Fracture ... and the site of fracture ... with clavicle fractures ... #Clavicular #Fracture ... #pathophysiology
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... bamboo spine) -> Fracture ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology ... signs #symptoms #diagnosis