The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs diagnosis anorexianervosa behavioraldisorder bulimianervosa msk pediatrics riskfactors syndrome 21hydroxylasedeficiency 21ohd acute adhd anxiety attentiondeficithyperactivedisorder compartmentsyndrome complications criteria depression endocrinology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... lateral hip Signs/Symptoms ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... Incr Skeletal fractures ... PraderWilli #Syndrome #genetics ... #pathophysiology ... #peds #pediatrics
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... suicide Other Symptoms ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
bleeding tendency/fracture ... CompartmentSyndrome #ACS ... #pathophysiology ... #orthopedics
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
have either 26 symptoms ... or restless • Acts ... as if "driven by ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
occur in utero as ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
Neurotic personality Genetics ... Psychological Symptoms ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... / Behavioural Features ... complications, such as ... BulimiaNervosa #pathophysiology ... #psychiatry
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
increased risk of fracture ... mortality rates of all psychiatric ... Complications #pathophysiology ... diagnosis #signs #symptoms ... #psychiatry
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