The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
activity -> Dose-dependent ... Sedation, dose-dependent ... #SideEffects #Pathophysiology
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
Dependent Personality ... self #DPD #Dependent ... #PersonalityDisorder
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
Antisocial Personality ... disorder #ASPD #Antisocial ... #PersonalityDisorder
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
, weakness - Dependence ... #Pharmacology #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
tissue • T cell-dependent ... cells • T cell-independent ... Humoral #Immunity #pathophysiology
Lewy Body Dementia: Pathogenesis and Clinical Findings
Lewy Body Dementia is a sub-category of major or mild
neurocognitive disorders depending ... LewyBody #Dementia #pathophysiology
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
symptoms varies depending ... Withdrawal #Opiate #Pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
of ER and AR -dependent ... Hyperplasia #Prostate #Pathophysiology
Major Depressive Disorder: Complications
 • Recurrent Depressive Episodes
 • Early parenthood
 • Social isolation and interpersonal
Substance abuse or dependence ... Complications #Pathophysiology
Charcot Joint - Neuropathic Arthropathy: Pathogenesis and Clinical findings
 • Impaired joint protection -> abnormal joint
pain (variable dependent ... #Arthropathy #pathophysiology