The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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symptoms pathophysiology psychiatry complications lupus erythematosus inhibitors sideeffects systemic centralretinalartery crao criteria extraarticular gastrointestinal mnemonic msk mucocutaneous musculoskeletal obsessivecompulsive occlusion
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Musculoskeletal Manifestations ... Myopathy (Also caused ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Erythematosus #SLE ... pathophysiology #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... hair follicles -> causes ... pathophysiology #diagnosis ... #signs #symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Dizziness - Nausea ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Viral replication causes ... swelling - GI Manifestations ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... inflammation tends to cause ... pathophysiology #signs ... #symptoms #diagnosis
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... Sores, scars, calluses ... inducing vomiting #BulimiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
GCA, SLE, GPA) - ... retinal edema caused ... ophthalmology #diagnosis ... #signs #symptoms
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
hormone levels cause ... Cardiac Arrest #BulimiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms
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