The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Viral replication causes ... Peripheral sensory changes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
others AVPD Mnemonic ... : CRINGES Dx: A ... AVPD #Avoidant #PersonalityDisorder ... #Diagnosis #Psychiatry ... #CRINGES
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... - Cognitive Changes ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... periumbilical region), nausea ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
- Cognitive Changes ... Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
, frequent job changes ... assault ASPD Mnemonic ... ASPD #Antisocial #PersonalityDisorder ... #Diagnosis #Psychiatry ... Signs #Symptoms #Mnemonic
Obsessive-Compulsive Personality Disorder (OCPD): Pathogenesis and Clinical Findings
 • Miserly - Lack of generosity when it
themselves; hoard in case ... value OCPD Mnemonic ... ObsessiveCompulsive #PersonalityDisorder ... #Diagnosis #Psychiatry ... Signs #Symptoms #Mnemonic
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
mental status changes ... ingestion and most cases ... make a clinical diagnosis ... Serotonin #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis