The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs symptoms psychiatry inhibitors obsessivecompulsive pharmacology sideeffects centralretinalartery complications crao criteria differential extraarticular henochscholeinpurpura hsp iga lupus mania manic manifestations
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings Psychological Hypothesis • Cognitive behavioral model: Emotional disturbance arising from
Hypotheses • Serotonin ... of postsynaptic serotonin ... consequences #OCPD ... ObsessiveCompulsive #PersonalityDisorder ... #Diagnosis #Psychiatry
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Selective Serotonin ... Side Effects • Serotonin ... Dizziness - Nausea ... #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine ... , Vomiting Serotonin ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... periumbilical region), nausea ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
Decrased central serotonin ... Manic #Secondary #Causes ... #Differential #Diagnosis ... #Pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
OCP, Protein C & ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... ingestion and most cases ... make a clinical diagnosis ... #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis
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