The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Pathophysiology #Pharmacology ... Psychiatry #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Pathophysiology #Pharmacology ... Psychiatry #Diagnosis #Signs ... #Symptoms
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Note: Opioid withdrawal ... life-threatening (exceptions being ... combined with withdrawal ... Pathophysiology #Diagnosis #Signs
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Allergic reaction -> Benign ... decr intake -> Withdrawal ... Pathophysiology #Psychiatry #Pharmacology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Extrapyramidal Symptoms ... AntiPsychotics #FirstGeneration ... #SideEffects #pharmacology
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
to use EtOH • Withdrawal ... symptoms - ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Psychiatry
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Benzodiazepine (BZD) withdrawal ... Asthma. or sense of being ... #pharmacology # ... pathophysiology #diagnosis #signs ... #symptoms
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
mood - Incr withdrawal ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Chalazion: a benign ... ophthalmology #diagnosis #signs ... #symptoms
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
almost always a benign ... Signs / Symptoms